Russell, 27, said he was eager to take to the track, with pre-season testing taking place in Bahrain from Wednesday until Friday.
“I feel like last year was my strongest in F1,” the British driver said.
“This coming season will be my seventh in the sport, and fourth with the works Mercedes team, and I’m working hard to improve year-on-year. As a team, we are incredibly motivated to improve on last season.”
Italian Antonelli, 18, said he was excited to make his F1 debut.
“It is a great opportunity, and I am very thankful to everyone at Mercedes for the faith and trust they’ve placed in me,” he said.
The opening race of the season, the Australian Grand Prix, takes place in Melbourne on 16 March.