THE AMD Instinct MI455X graphics processing unit is designed for frontier AI and AI factory deployments. It is part of the AMD Instinct MI400 Series, which helps organizations deploy, scale and manage AI and HPC workloads.
PHOTOGRAPH COURTESY OF AMD
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AMD has unveiled its Instinct MI400 Series GPUs, a new generation of data center accelerators designed to power frontier artificial intelligence (AI) and high-performance computing (HPC).
Introduced during Advancing AI 2026, the lineup includes the Instinct MI455X for hyperscale AI factories and large-scale AI deployments, and the Instinct MI430X for sovereign AI and scientific computing.
The new GPUs feature HBM4 high-bandwidth memory, advanced security capabilities and AMD’s open ROCm software platform, enabling organizations to deploy and scale AI workloads without vendor lock-in.
According to AMD, the MI455X is optimized for large-model training and AI inference, while the MI430X delivers up to 288 TFLOPS of FP64 performance for scientific and HPC applications.
The company said the MI400 Series also supports secure boot, encrypted GPU-to-GPU communication and scalable system architectures, allowing customers to build AI infrastructure for everything from national research centers to hyperscale AI factories.
