Australian Open champion Madison Keys became the latest high-profile casualty at Wimbledon, falling to unseeded German Laura Siegemund in a straight-sets third-round upset on Friday.

Keys, the tournament's No. 6 seed, was outplayed on Court Two, losing 6-3, 6-3 to the 104th-ranked Siegemund. The 30-year-old American struggled throughout the match, committing 31 unforced errors in a performance that ended her bid for a deeper run at the All England Club.

The loss makes Keys the fifth top-six seed in the women's draw to exit before the fourth round, following earlier departures by Coco Gauff, Jessica Pegula, Jasmine Paolini and Zheng Qinwen. World No. 1 Aryna Sabalenka remains in contention.

It was a disappointing Fourth of July for Keys, who captured her first Grand Slam title in January by defeating Sabalenka at the Australian Open but has never advanced beyond the quarterfinals in 11 Wimbledon appearances.

Siegemund, 37, reached the round of 16 at Wimbledon for the first time in her career. The veteran previously made her deepest Grand Slam run at the 2020 French Open, where she reached the quarterfinals.

“When you beat a great player like Madison you have to be really happy,” Siegemund said. “I managed to keep my nerve in the end. If you don’t have nerves in this moment you are probably dead.”

Siegemund, who defeated former U.S. Open finalist Leylah Fernandez in the second round, is now the oldest woman remaining in the singles draw.