When hormones stand in the way: Infertility through an endocrine lens
In the Philippines, studies estimate that about 10 to 15 percent of couples experience infertility, reflecting global statistics.

Infertility is more common than many people realize, yet it remains a topic often discussed in hushed tones. Medically, infertility is defined as the inability to conceive after one year of regular, unprotected intercourse — or after six months if the woman is over 35. Behind this clinical definition are real couples facing uncertainty, disappointment, and deep longing.
In the Philippines, studies estimate that about 10 to 15 percent of couples experience infertility, reflecting global statistics. This means roughly one in seven couples may struggle to conceive. A substantial proportion of these cases are linked to hormonal or endocrine disorders — an area in which modern medicine offers genuine hope.
PCOS is one of the most common endocrine causes of infertility in Filipino women.
Photograph courtesy of Compass Oncology
Endocrinology, the study of hormones, lies at the heart of fertility. Hormones regulate ovulation, menstrual cycles, sperm production, and the uterine environment. When these chemical messengers become imbalanced, conception can be challenging — but often not impossible.
I understand this not only as an endocrinologist, but also as a patient.
Early in my marriage, my husband and I tried to conceive without success. Month after month passed, bringing growing anxiety. As a physician, I recognized that something was wrong, but knowledge does not make waiting easier. After a thorough evaluation, I was diagnosed with polycystic ovary syndrome (PCOS), a hormonal condition that disrupts ovulation. Suddenly, the irregular cycles and subtle symptoms I had previously dismissed made sense. With proper treatment and guided care, my hormones stabilized, ovulation resumed, and in time, we were blessed with our eldest son. That journey deepened my empathy for every patient who sits across from me carrying the same quiet fear: What if it never happens for us?


