GENEVA, Switzerland (AFP) — The World Health Organization (WHO) on Friday published for the first time directives to improve the prevention, detection and treatment of infertility, which affects millions across the globe.

“One in six people worldwide experience infertility during their lifetime,” said Pascale Allotey, the global health body’s head of sexual and reproductive health.

“The condition affects individuals and couples across all regions and income levels. And yet access to safe and affordable care remains highly inequitable.”

Allotey told reporters that the issue of infertility had been neglected “for far too long.”

The new guide would provide a “unified, evidence-based foundation” to ensure care is safe, effective and accessible for all, she added.

According to the WHO, infertility is a condition of the male and female reproductive system, defined as the inability to achieve pregnancy after 12 months or more of regular unprotected sexual relations.

The situation can lead to major distress, stigmatization and financial difficulties.

In several countries, most of the cost of infertility tests and treatment is borne by patients, which often leads to “catastrophic financial expenditures.”